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玫瑰茄(Hibiscus sabdariffa Linn.)(英名 Roselle)系锦葵科木槿属的草本植物,热带、亚热带地区已广泛栽培。本实验采用厦门、同安一带的玫瑰茄花萼制成煎剂、醇提液和浸剂,对7只正常麻醉犬静脉注射200mg/kg,使血压急剧下降,收缩压由137mmHg 下降至68mmHg,降压幅度为原水平的50%以上,维持作用时间6～12分钟。除醇提液外,不同pH 的玫瑰茄不影响其降压效果。2只清醒肾型高血压犬,每日灌胃玫瑰茄煎剂4g/kg,疗程
Hibiscus sabdariffa Linn (Hiscus sabdariffa Linn.) (named Roselle) is a herb of the genus Malvaceae, which has been widely cultivated in tropical and subtropical regions. In this experiment, the decoction, alcohol extract and infusion of roselle calyx from Xiamen and Tongan were used. The intravenous injection of 200 mg/kg to 7 normal anesthetized dogs caused a sharp drop in blood pressure. The systolic blood pressure dropped from 137 mmHg to 68 mmHg. The amplitude is more than 50% of the original level and the duration of action is 6 to 12 minutes. In addition to alcohol extracts, roselle with different pH does not affect its antihypertensive effect. 2 awake kidney-type hypertensive dogs, daily irrigate Roselle decoction 4g/kg, course of treatment