近年来,由于脑脊液(CSF)细胞收集方法的改进,CSF细胞学检查已成为研究神经系统疾病不可缺少的手段之一,越来越受到临床多学科的重视。众所周知,白血病是造血系统的恶性肿瘤。随着联合化疗的进展,白血病患者的生存期延长了。但由于颅内有血脑屏障的存在,使得中枢神经系统(CNS)成为 In recent years, CSF cytology has become an indispensable means of studying the nervous system diseases due to the improvement of CSF collection methods, and has been paid more and more attention by clinical multidisciplinary. As we all know, leukemia is a malignant tumor of the hematopoietic system. With the progress of combination chemotherapy, leukemia patients have prolonged survival. However, due to the presence of a blood-brain barrier in the brain, the central nervous system (CNS) becomes