朝鲜蓟(Cynara Scolymus.L.)亦称 Artichoke,属菊科,为二年生草本植物,盛产于欧洲。早在十八世纪,当地民间就用简单的方法,将其叶和根煮汁来治疗肝脏病。到二十世纪以后,始逐步阐明其药理作用,意大利、法国、罗马尼亚等国家先后将本品加工提取做成适当的制剂用以治疗慢性肝、胆疾病,综合各有关方面的文献报道,朝鲜蓟具有利胆、利尿、促进胆固醇代谢及抗消化器官过敏等作用。其有效成分大体上有两类,其一为咖啡酸类的邻-二羟基酚衍生物;另一类为含木犀草素的黄酮甙,绝大部分存在于叶子内。虽然国外早已报道分离出具有利胆作用的主要成分莱蓟素(Cynarine)为1,5-二咖啡奎宁酸酯并加以人工合成,但另据报道,单纯的莱蓟素结晶,疗效并不理想,说明朝鲜蓟的治疗作用系属几种成分的协同作 Cynara Scolymus (L.), also known as Artichoke, belongs to the family Asteraceae and is a biennial herb that is abundant in Europe. As early as the 18th century, the local people used simple methods to cook their leaves and roots to treat liver diseases. After the 20th century, its pharmacological effects were gradually elucidated. Countries such as Italy, France, and Romania successively extracted and processed the product into appropriate preparations for the treatment of chronic liver and gallbladder diseases. Comprehensive literature reports from relevant parties, artichokes With gallbladder, diuretic, promote cholesterol metabolism and anti-digestive organ allergies. There are generally two types of active ingredients, one of which is an ortho-dihydroxyphenol derivative of caffeic acid; the other is a flavonoid glycoside containing luteolin, most of which is present in leaves. Although it has long been reported abroad that the main component of choleretic action, cyclamate (Cynarine) is 1,5-di- coffee quinine diacetate, and it has been artificially synthesized, it has also been reported that the effect of pure selenoquine crystals is not satisfactory. , indicating that the therapeutic effect of artichoke is a synergistic combination of several components