临床应用奎尼丁的盐类很多。其中奎尼丁葡萄糖醛酸盐(QG)是1957年推荐口服的。本文以 QG 作为长效盐的例子,详细介绍。其一般原理亦适用于其他长效或短效制剂。QG 片剂中配有特殊处理的氢化植物油基质,药物可以逐渐释放。适应症:(1)房性心律失常:心房颤动或扑动的患者在直流电电击治疗前可用 QG。其理由有二:①有些患者用小剂量奎尼丁即可转变为窦性心律;②使电击更有效,心律转 Clinical application quinidine a lot of salt. Quinidine glucuronate (QG) which was recommended oral administration in 1957. In this paper, QG as an example of long-acting salt, described in detail. Its general principle also applies to other long-acting or short-acting agents. QG tablets are formulated with a specially treated hydrogenated vegetable oil base that gradually releases the drug. Indications: (1) atrial arrhythmia: atrial fibrillation or flutter in patients with DC shock treatment available QG. There are two reasons: ① Some patients with small doses of quinidine can be transformed into sinus rhythm; ② make the shock more effective, rhythm of heart