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目的调查我院清洁手术围手术期抗菌药物的使用情况,进行预防性用药的合理性分析,以提高合理用药水平。方法回顾性调查2008年7～12月符合遴选标准的围手术期患者216例,对临床预防性应用抗菌药物的合理性进行分析评价。结果216例围手术期患者手术切口均为1类切口,抗菌药物应用率为100%,涉及7大类。经综合分析,不合理用药主要表现为术前用药时间不当,术后用药时间过长,选药档次过高,用药剂量过大等等。结论我院围手术期抗菌药物的应用普遍存在不合理现象,应严格遵守《抗菌药物临床应用指导原则》,规范围手术期抗菌药物的应用,提高抗菌药物合理应用的水平。
Objective To investigate the use of perioperative antibacterials in clean operation in our hospital and to analyze the rationality of preventive medication in order to improve the rational use of drugs. Methods A retrospective survey of 216 cases of perioperative patients who met the selection criteria from July to December in 2008 was carried out to evaluate the rationality of prophylactic antibiotics. Results 216 cases of perioperative surgical incision were all type 1 incision, antimicrobial drug application rate was 100%, involving 7 categories. After a comprehensive analysis, irrational use of drugs mainly manifested as inappropriate preoperative medication time, medication time is too long, high drug grade, dosage is too large and so on. Conclusions The perioperative application of antimicrobial agents in our hospital is generally unreasonable. We should strictly abide by the Guiding Principles of Clinical Application of Antibacterials, regulate the application of perioperative antibiotics, and improve the rational use of antimicrobial agents.