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本文重点介绍了选择性清洁肠道疗法的理论基础及其在外科急危重病人中临床应用的研究进展。近年来的临床观察表明,该治疗方法可有效地拮抗潜在性 G~-致病菌在宿主体内的定植,显著降低危重病人继发性医院内感染(尤其是呼吸道感染)的发病率,并能控制 G~-耐药菌株的流行。但是,目前多数报道对患者预后改善尚不明显,仍有许多异议,有待于进一步研究。其主要适应证为严重创伤、器官移植患者及高度 G~-耐药菌感染。
This article focuses on the theoretical basis of selective cleansing of intestinal tract and its clinical application in acute critically ill patients. In recent years, clinical observation shows that this treatment method can effectively antagonize the potential of G ~ - colonization in the host body, significantly reduce the incidence of secondary hospital infections (especially respiratory infections) in critically ill patients, and can Control G - - drug-resistant strains of the epidemic. However, at present, most reports on the prognosis of patients is not yet obvious improvement, there are still many objections, pending further study. The main indications for severe trauma, organ transplant patients and highly G ~ - resistant bacteria infection.