目的对2007年2月至2010年3月期间来我院就诊,临床疑为先天愚型的患者进行外周血染色体检查。方法用培养基培养外周血淋巴细胞,G显带进行染色体核型分析。结果检出唐氏综合征患者275例,其中单纯型247例,易位型21例,嵌合型7例。 Objective To carry out peripheral chromosomal examinations in our hospital from February 2007 to March 2010 with clinical suspicion of Down’s syndrome. Methods Peripheral blood lymphocytes were cultured with culture medium and G banding was performed for karyotype analysis. Results 275 cases of Down syndrome were detected, of which 247 were simple type, 21 were translocation type and 7 were chimerism type.