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目的了解艾滋病抗病毒治疗后对CD 4+T淋巴细胞计数的影响,评价治疗效果。方法选取在泉州市疾控中心接受抗病毒治疗满1年以上的HIV/AIDS患者40例为研究对象,收集患者的CD 4+T淋巴细胞、HIV病毒载量以及因服药引起的副反应等资料进行分析。结果与基线比较,患者CD 4+T淋巴细胞绝对计数治疗3、6、9、12、15、18个月后均有增长,以6个月内增速较快,7~15个月增长趋于平缓,到第15个月平均增加了133个/μL,第18个月平均增加183个/μL;多数患者病毒载量低于检测限。结论抗病毒治疗能明显改善艾滋病病人免疫状况,CD 4+T淋巴细胞计数上升明显,重建病人免疫系统,延缓艾滋病进程。
Objective To understand the effect of AIDS antiviral treatment on CD4 + T lymphocyte count and evaluate the therapeutic effect. Methods Forty patients with HIV / AIDS who were treated with antiviral therapy for more than one year in Quanzhou Center for Disease Control and Prevention were enrolled as study objects. CD 4 + T lymphocytes, HIV viral load and side effects caused by medication were collected Analyze. Results Compared with baseline, the absolute counts of CD 4 + T lymphocytes increased after 3, 6, 9, 12, 15 and 18 months of treatment, with a rapid growth within 6 months and an increase of 7 to 15 months On average, by the 15th month an average increase of 133 cells / μL was achieved, with an average increase of 183 cells / μL in the 18th month. The majority of patients had viral load below the limit of detection. Conclusion Antiviral therapy can significantly improve the immune status of AIDS patients, CD 4 + T lymphocyte counts increased significantly, to rebuild the patient’s immune system and delay the AIDS process.