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目的:观察米非司酮用于紧急避孕的临床效果及对月经的影响。方法:将要求紧急避孕的140例妇女按照随机分组的方式分为观察组和对照组,分别各70例。对照组口服左炔诺孕酮片,观察组口服米非司酮片,观察两组临床效果及不良反应,并对比用药后对月经的影响。结果:从紧急避孕的临床效果和用药期间不良反应发生率对比,均无统计学意义(P>0.05),从用药后对月经的影响对比,观察组妇女的月经延迟率及月经过多率较对照组低,组间对比,差异有统计学意义(P<0.05)。结论:采用米非司酮进行紧急避孕具有较高的安全性和有效性,且对月经周期及月经量影响小。
Objective: To observe the clinical effect of mifepristone for emergency contraception and its effect on menstruation. Methods: 140 women who requested emergency contraception were randomly divided into observation group and control group, 70 cases in each. The control group was given levonorgestrel tablets orally, and the observation group was given mifepristone tablets orally. The clinical effects and adverse reactions of the two groups were observed and the effects on the menstrual period were compared. Results: There was no significant difference between the clinical effect of emergency contraception and the incidence of adverse reactions during the treatment (P> 0.05). The comparison of the effects on menstruation after treatment showed that the delay rate of menstruation and the excess rate of menstruation in the observation group The control group was low, contrast between groups, the difference was statistically significant (P <0.05). Conclusion: The use of mifepristone for emergency contraception has high safety and effectiveness, and has little effect on menstrual cycle and menstrual flow.