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目的探讨门冬胰岛素(诺和锐)治疗妊娠糖尿病的临床疗效以及安全性。方法将我院2009年3月至2011年4月收治的妊娠糖尿病患者100例,随机分为对照组与治疗组,每组50例,对照组给予诺和灵30R治疗,观察组给予诺和锐治疗。检测2组治疗前后的空腹血糖(FPG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)变化,观察2组治疗对妊娠结局的影响。结论门冬氨酸治疗妊娠糖尿病的临床疗效确切,对母婴的影响较小,值得推广应用。
Objective To investigate the clinical efficacy and safety of insulin aspart (Novartis) in the treatment of gestational diabetes mellitus. Methods 100 cases of gestational diabetes mellitus treated in our hospital from March 2009 to April 2011 were randomly divided into control group and treatment group, with 50 cases in each group. The control group was given Novolin 30R, treatment. The fasting blood glucose (FPG), postprandial 2h blood glucose (2hPG) and HbA1c were measured before and after treatment to observe the effect of the two groups on pregnancy outcome. Conclusion Aspartic acid treatment of gestational diabetes clinical efficacy is exact, less impact on mother and baby, it is worth promoting the application.