我院2006年2月14日,娩出一新生儿,通过病史、体检、辅助检查和染色体核型分析,确诊为18-三体综合征。患儿女,第二胎第二产,胎龄43周,顺产出生。胎膜早破6h,羊水Ⅲ°污染,胎盘钙化。1、5、10分钟Apgar评分分别为6、7、8分,复苏后仍有呼吸困难、哭声弱,转儿科。追问病史,母亲孕2+ Our hospital February 14, 2006, delivered a newborn, through medical history, physical examination, laboratory examinations and chromosome karyotype analysis, diagnosed as 18-trisomy syndrome. Children with children, the second child of the second child, gestational age 43 weeks, birth was born. Premature rupture of membranes 6h, amniotic fluid Ⅲ ° pollution, placental calcification. Apgar scores of 1, 5 and 10 minutes were 6, 7 and 8 respectively. After resuscitation, there were still breathing difficulties, weaker crying sounds, and pediatrics. Asked history, mother pregnant 2+