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目的：评估１４Ｃ－ 尿素呼吸试验（以下简称１４Ｃ－ ＵＢＴ）诊断幽门螺杆菌（ＨＰ）感染的可靠性。方法：９２例有消化道症状而作胃镜的患者进行粘膜活检行快速尿素酶试验、组织学检查、血清ＣａｇＡ抗体测定以及１４Ｃ－ ＵＢＴ。结果１４Ｃ－ ＵＢＴ的敏感性为９６．１５％ ，特异性９０．０％ ，结论１４Ｃ－ ＵＢＴ是诊断ＨＰ感染的可靠而又无创伤的诊断方法。
OBJECTIVE: To assess the reliability of 14C-urea breath test (hereinafter referred to as 14C-UBT) for diagnosis of Helicobacter pylori (HP) infection. Methods: Ninety-two patients with gastrointestinal symptoms underwent endoscopic mucosal biopsy with rapid urease test, histological examination, serum CagA antibody assay, and 14C-UBT. Results The sensitivity and specificity of 14C-UBT were 96.15% and 90.0% respectively. Conclusions 14C-UBT is a reliable and noninvasive diagnostic method for diagnosing HP infection.