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目的研究骨关节炎发病的影响因素,为骨关节炎的预防控制提供科学依据。方法应用1∶1配对病例对照研究方法,从济宁市及兖州的4所医院调查108例骨关节炎患者,以性别相同、年龄相近(±2岁以内)作为配对条件选择对照108例,收集相关的资料进行单因素、多因素条件Logistic回归分析。结果体质指数、饮酒和关节外伤史均与骨关节炎呈正相关,OR(95%CI)分别为2.62(1.11～6.19),11.88(2.27～62.14),15.41(2.05～115.96),日照、食用豆制品、新鲜蔬菜和水果是骨关节炎的保护因素,OR(95%CI)分别为0.30(0.13～0.69)、0.10(0.02～0.47)、0.07(0.02～0.30)和0.35(0.13～0.98)。结论肥胖、饮酒和关节外伤史均为骨关节炎的危险因素,多摄入新鲜蔬菜、新鲜水果、豆制品、多晒太阳则是骨关节炎的保护性因素。
Objective To study the influencing factors of the pathogenesis of osteoarthritis and provide a scientific basis for the prevention and control of osteoarthritis. Methods A one-to-one paired case-control study was conducted. 108 patients with osteoarthritis were investigated in 4 hospitals in Jining City and Yanzhou City. 108 males with the same sex and similar age (± 2 years old) The data were univariate, multivariate conditional logistic regression analysis. Results The body mass index, alcohol consumption and history of joint trauma were all positively correlated with osteoarthritis. The OR (95% CI) were 2.62 (1.11-6.19), 11.88 (2.27-62.14), 15.41 (2.05-115.96), sunshine, Products, fresh vegetables and fruits were the protective factors of osteoarthritis. OR (95% CI) were 0.30 (0.13-0.69), 0.10 (0.02-0.47), 0.07 (0.02-0.30) and 0.35 (0.13-0.98) respectively. Conclusion The history of obesity, alcohol consumption and joint trauma are the risk factors of osteoarthritis. More intake of fresh vegetables, fresh fruits, soy products and more sun are the protective factors of osteoarthritis.