目前,由于常用的食管癌检测标志物敏感性低、特异性差,无法实现早期诊断目的,所以挖掘新的理想血清标志物成为研究热点。本文对食管癌血清中肿瘤相关自身抗体的筛选和检测价值进行了概括,证实了利用其进行食管癌早期检测具有较高的诊断价值,为食管癌肿瘤标志物的研究提供了新的方向。 At present, due to the low sensitivity and specificity of commonly used esophageal cancer detection markers, early diagnostic purposes cannot be achieved, so the search for new ideal serum markers has become a research hotspot. This article summarizes the screening and detection value of tumor-associated autoantibodies in the serum of esophageal cancer, and confirms that the use of it for the early detection of esophageal cancer has a higher diagnostic value, and provides a new direction for the study of esophageal cancer tumor markers.