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目的 探讨妊娠晚期妇女凝血四项的变化及临床意义.方法 选取我院2018年1月到5月住院的170例妊娠晚期妇女作为观察组,156名非妊娠健康体检妇女作为对照组,两组分别进行凝血四项的检测,包括凝血酶原时间(PT),活化部分凝血活酶时间(APTT),凝血酶时间(TT)及纤维蛋白原(FIB).结果 对凝血四项指标进行统计学对比分析,观察组PT、APTT和TT显著低于对照组,而FIB则高于对照组,差异具有统计学意义(P＜0.05).结论 妊娠晚期妇女应尽早监测凝血功能,对临床评估,治疗和预防产后出血及弥散性血管内凝血(DIC)的发生有着重要作用.“,”Objective to study the changes and clinical significance of blood coagulation in late pregnant women.Methods We select 170 cases late pregnancy women in our hospital from January 2018 to May as observation group,156 health check-up of women as the control group.Blood coagulation was detected in both groups,including the prothrombin time(PT),activated partial thrombin time live enzymes(APTT),thrombin time(TT)and fibrinogen(FIB).The two groups of indexes were statistically analyzed separately.Results APTT and TT in the observation group were significantly lower than that in the control group,while FIB was higher than that in the control group,.The difference was statistically significant(P＜0.05).Conclusion Blood coagulation functions should be monitored early in late pregnant women,which plays an important role in clinical evaluation,treatment and prevention of postpartum hemorrhage and disseminated intravascular coagulation(DIC).