报道3例称为中线肉芽肿病人的临床特征以及该病的免疫表现型研究。结果显示该病的组织病理学检查为多形态细胞浸润,正常组织结构破坏,形成坏死和血管炎。浸润的细胞有小细胞、大细胞、混合型细胞、上皮细胞和组织细胞,而浆细胞罕见。采用单克隆抗体免疫组化检查时则发现非典型性细胞和浸润细胞的绝 Reported the clinical features of 3 patients known as midline granuloma and the immunophenotype of the disease. The results showed that the pathological examination of the disease for polymorphic cell infiltration, destruction of normal tissue structure, the formation of necrosis and vasculitis. Infiltrating cells are small cells, large cells, mixed cells, epithelial cells and tissue cells, and rare plasma cells. Monoclonal antibody immunohistochemical examination found atypical cells and infiltrating cells must