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为了研究肺结核的化疗时间是否可进一步缩短,作者对60例晚期肺结核病例进行短程强力化疗的临床试验。男性35例,女性25例,年龄16～66岁(平均26.8岁)。X线检查:58例为空洞性肺结核,2例未见空洞。细菌学检查:痰液涂片结核菌阴性而培养阳性者24例,痰液涂片和培养均为阳性者36例。治疗:每天给予异烟肼(300mg/日)、利福平(450mg/日)、乙胺丁醇(800～1200mg/日)和链霉素(0.75～1。0g/日),连用3～6月,直至痰结核菌转阴,空洞闭合,75%的病变吸收。然后再单用异烟肼治疗1年
In order to study whether chemotherapy can be further shortened, the author of 60 cases of advanced pulmonary tuberculosis cases of short-term strong chemotherapy in clinical trials. 35 males and 25 females, aged 16 to 66 years (mean, 26.8 years). X-ray examination: 58 cases of empty tuberculosis, no empty in 2 cases. Bacteriological examination: smear mycobacterium smegmatis negative and cultured positive in 24 cases, sputum smear and culture were positive in 36 cases. Treatment: Isoniazid (300 mg / day), rifampin (450 mg / day), ethambutol (800-1200 mg / day) and streptomycin (0.75-1.0 g / June, sputum TB until negative, empty closed, 75% of the lesions absorbed. And then single isoniazid treatment for 1 year