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目的:观察醒神汤联合常规西医疗法治疗急性缺血性脑卒中痰湿蒙神证患者的疗效。方法:将102例急性缺血性脑卒中痰湿蒙神证患者随机分为对照组和观察组各51例。对照组给予吸氧与呼吸支持,控制血压、血糖,营养支持,改善脑血循环及保护神经等综合处理,观察组在对照组治疗的基础上加用醒神汤治疗,2组疗程均14天。治疗前后评定2组患者的美国国立卫生研究院卒中量表(NIHSS)评分、痰湿蒙神证评分,采用Barthel指数(BI)评价日常生活能力,采用Ashworth痉挛评定量表评价肢体痉挛程度。结果:观察组总有效率为92.16%,对照组为76.47%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组NIHSS评分、Ashworth评分和痰湿蒙神证评分均较治疗前下降,BI较治疗前升高,差异均有统计学意义(P<0.01);观察组NIHSS评分、Ashworth评分和痰湿蒙神证评分均低于对照组,BI高于对照组,差异均有统计学意义(P<0.01)。结论:在西医常规治疗的基础上采用醒神汤治疗急性缺血性脑卒中痰湿蒙神证患者,能有效减轻神经功能缺损程度,改善临床症状,缓解肢体痉挛程度,提高患者的生活自理能力,临床疗效优于单纯西医治疗
OBJECTIVE: To observe the therapeutic effect of Xingshen Decoction combined with conventional western medicine on patients with phlegm-dampness syndrome of acute ischemic stroke. Methods: A total of 102 patients with phlegm-dampness syndrome of acute ischemic stroke were randomly divided into control group and observation group of 51 patients. The control group was given oxygen and respiratory support, blood pressure, blood glucose, nutritional support, improve cerebral blood circulation and protect the nerves and other comprehensive treatment, the observation group in the control group based on the treatment plus Xing God Decoction treatment, two groups of treatment were 14 days. Before and after treatment, NIHSS score, Phlegm-dampness and Shennong card score were evaluated in two groups of patients. Barthel index (BI) was used to evaluate the daily living ability. Ashworth’s spasm rating scale was used to evaluate the degree of limb spasticity. Results: The total effective rate was 92.16% in the observation group and 76.47% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the scores of NIHSS, Ashworth and Phlegm-dampness syndrome in two groups were lower than those before treatment, and BI was higher than before treatment (P <0.01); NIHSS score, Ashworth score and Phlegm - dampness and Shen - card score were lower than the control group, BI higher than the control group, the difference was statistically significant (P <0.01). Conclusion: Based on the conventional treatment of Western medicine, Xingshen Decoction can treat patients with phlegm-dampness and Shen-Shen syndrome of acute ischemic stroke, which can effectively reduce the degree of neurological deficits, improve clinical symptoms, relieve the degree of limb spasm and improve the self-care ability of patients , Clinical efficacy is better than Western medicine treatment