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本文研究盐酸纳美芬对小鼠吗啡身体依赖的拮抗作用。选用连续３ｄ给吗啡成瘾的小鼠用纳洛酮进行催瘾，记录催瘾后小鼠跳跃次数，结果表明，ｓｃ纳美芬０．０５—０．４ｍｇ·ｋｇ－１，能够完全拮抗小鼠对吗啡形成的身体依赖。
In this paper, nalmefene hydrochloride on mice morphine-dependent antagonism. Mice who were addicted to morphine for three consecutive days were induced to addicted to naloxone, and the number of mice jumping after the addiction was recorded. The results showed that scalphamate 0.05-0.4 mg · kg-1 could completely antagonize the small Rat dependence on the body formed by morphine.