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5. Synthesis and Antibacterial Activity of New Cephalosporin Compounds

Synthesis and Antibacterial Activity of New Cephalosporin Compounds

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：nana119

【摘 要】

：

Five new cephalosporin compounds were designed and synthesized, and the antibacterial activities were evaluated by the standard serial 2-fold agar dilution meth

【作 者】

：

De Cai FU Feng Ming CHU Zong R 

【机 构】

：

College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shij

【出 处】

：

中国化学快报（英文版）

【发表日期】

：

2005年10期

【关键词】

：

Cephalosporin synthesis antibacterial activities 

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论文部分内容阅读

Five new cephalosporin compounds were designed and synthesized, and the antibacterial activities were evaluated by the standard serial 2-fold agar dilution method in vitro.The results showed that the activities of the compounds Ⅰa and Ⅰb against ESBL E. coli and K.pneumoniae are comparable to those of Cefepime.

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