肺隐球菌病(pulmonary Cryptococcosis)是由新型隐球菌引起的亚急性或慢性肺部真菌病,首次由Sheppe等在1924年报告。免疫缺损或免疫抑制的病人易患,且可播散全身,产生中枢神经系统和其他器官的感染。新型隐球菌侵入健康者肺部,病变局限于肺内者称为原发性肺隐球菌病,临床诊断困难,容易误诊。曾有2例分别在手术前诊为肺癌和肺结核,手术标本病理证实为肺隐球菌病。 Pulmonary Cryptococcosis, a subacute or chronic pulmonary mycosis caused by Cryptococcus neoformans, was first reported by Sheppe et al in 1924. Patients with immunodeficiency or immunosuppression are predisposed and can spread throughout the body, producing infections of the central nervous system and other organs. Cryptococcus neoformans invaded healthy lungs, lesions confined to the lungs known as primary pulmonary cryptococcosis, clinical diagnosis difficult, easy misdiagnosis. There were two cases were diagnosed before surgery for lung cancer and pulmonary tuberculosis, surgical specimens confirmed pathological pulmonary cryptococcosis.