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1982～1985年在新疆、宁夏等地共记录人体多房棘球蚴病142例,其中男72,女70。最大年龄69岁,最小12岁,而30～40岁组65例(47％)。人体9例病理标本主要呈巨块型和巨块结节型病肝,质地坚硬。切片显示病肝纤维化,其间有大小不等的肉芽结节病变,近中央处有坏死空洞。多房蚴由许多细小泡囊组成。角质膜较厚,生发层脱落不见,缺原头节,全系不育囊。囊腔有豆渣样碎屑,无囊液。 宁夏固源流行区自然动物宿主调查发现中华鼢鼠(Myospalax fontanieri)是本虫宿主新记录,自然感染率0.3％。达乌尔黄鼠(Citellus dauricus alaschanicus)自然感染率为1.3％。二种鼠类的多房蚴发育状况良好,质软有丰富的次生泡囊和原头节。中华鼢鼠有60～80％的育囊,达乌尔黄鼠有40～60％的育囊。二者切片所见泡囊角质层薄,有断裂;生发层较厚,发育有原头节并有群多的石灰质颗粒。组织病变有炎症白细胞浸润,并有成纤维细胞和结缔组织增生以及肉芽肿病变,肝组织绝大部分被次生囊所取代。观察证明两种鼠类是我国多房棘球蚴的适宜动物宿主。 小白鼠人工感染实验阐明虫卵至多房棘球蚴的全程发育。感染孕节48小时后肝组织内有六钩蚴病灶。3天后虫体呈囊块,与肝组织有界限可辨。10～12天后虫体形成泡囊,有生发层细胞分化。30天后泡囊增大达1.3×1.0?
From 1982 to 1985 in Xinjiang, Ningxia and other places recorded a total of 142 cases of human polymyalgia echinococcosis, male 72, female 70. The oldest was 69 years old and the youngest was 12 years old, compared with 65 cases (47%) in the 30-40 years old group. Nine human pathological specimens were mainly massive and massive nodular disease liver, hard texture. Slices showed diseased liver fibrosis with granulomatous lesions ranging in size and necrosis near the center. Many cells are composed of many tiny vesicles. Thick cuticle, hair layer off missing, missing the original head, the Department of sterile bags. Cystic cavity debris, no cyst fluid. Natural animal hosts in Guyuan endemic area of Ningxia found that Myospalax fontanieri is a new record of this insect host with a natural infection rate of 0.3%. Natural infection rate of Citellus dauricus alaschanicus was 1.3%. The two rodents have a well-developed metacercaria, which is soft and rich in secondary vesicles and prototheca. Chinese zokor has 60 to 80% of the cysts, Daurian ground squirrels have 40 to 60% of the cysts. Sections of the two see the vesicle stratum corneum thin, broken; germinal layer thick, the development of the original head section and a large number of limestone particles. Inflammatory leukocyte infiltration of tissue lesions, and fibroblasts and connective tissue hyperplasia and granulomatous lesions, most of the liver tissue was replaced by secondary capsule. Observation shows that two kinds of mice are suitable for multi-room echinococcosis animal host. Artificial infection experiments in mice to clarify the entire development of the egg to the room echinococcosis. 48 hours after infection during pregnancy, there are six cystic lesions in liver tissue. 3 days after the body was a capsule, with a clear distinction between the liver tissue. After 10 ~ 12 days, the body forms vesicles and the germinal layer cells differentiate. After 30 days the vesicles increased by 1.3 × 1.0?