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近年来,我院收治棉酚中毒致远端肾小管酸中毒7例。患者均来自棉区,年龄17～50岁,进食粗制棉子油2～10年。主要临床表现为口渴、多尿、恶心呕吐及低血钾症状(肢体无力、对称性软瘫、肌张力减退、腱反射减弱或消失)。化验检查血清钾<3.1m Eq/L,尿pH>7.0,24小时尿钾增高,BE负值>-3.8m Eq/L,H CO_3~-<20m Eq/L,心电图示低血钾表现(ST段压低,T波低平倒
In recent years, our hospital received gossypol poisoning caused by distal renal tubular acidosis in 7 cases. Patients were from the cotton area, aged 17 to 50 years old, eating crude cottonseed oil 2 to 10 years. The main clinical manifestations are thirst, polyuria, nausea, vomiting and symptoms of hypokalemia (limb weakness, symmetrical paralysis, hypotonia, reduced or disappeared tendon reflexes). Laboratory tests of serum potassium <3.1m Eq / L, urine pH> 7.0,24 hours urinary potassium increased, BE negative> -3.8m Eq / L, H CO_3 ~ - <20m Eq / L, ECG showed hypokalemia ( ST segment depression, T wave down flat down