新近推出的大部份抗生素的规划注重于提高抗革蓝氏阴性菌的微生物活性。然而,抗阴性菌活性的提高似乎导致了抗革蓝氏阳性菌活性的降低。因此,相对来讲,在一个较小的范围内,许多较新的β-内酰胺类抗生素(青霉素类、头孢菌素类、青霉烯类、单酰胺菌素类)和氟化α-羟基喹啉抗革蓝氏阳性菌的活性较弱。然而,临床上遇到之主要致病菌正是多重革蓝氏阳性耐药菌。特别出现在三期护理的医院中。 Most of the newly introduced antibiotic programs focus on increasing the microbial activity against Gram-negative bacteria. However, the increase in anti-negative bacteria activity appears to result in a decrease in the activity of anti-gram-positive bacteria. Thus, relatively speaking, to a lesser extent, many of the newer beta-lactam antibiotics (penicillins, cephalosporins, penicillins, monoammoxins) and fluorinated alpha-hydroxy Quinoline anti-gram-positive bacteria activity is weak. However, the major pathogens encountered clinically are multiple Gram-positive bacteria. Especially in the three hospital care.