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目的探讨急性冠脉综合征(ACS)患者心率振荡(HRT)的变化及其临床意义。方法将100例冠心病患者分为2组:ACS组60例和稳定性心绞痛(SAP)组40例,另选同期30例冠状动脉造影正常者为对照组。采用24 h动态心电系统获得其室性早搏,分别计算3组振荡初始(TO)和振荡斜率(TS)2个指标。结果 ACS组TO明显高于SAP组和对照组(P<0.01),而TS则显著低于SAP组和对照组(P<0.01)。结论 ACS患者存在异常的HRT现象,猝死风险较高。
Objective To investigate the changes of heart rate oscillations (HRT) in patients with acute coronary syndrome (ACS) and its clinical significance. Methods 100 patients with coronary heart disease were divided into two groups: ACS group (60 cases) and stable angina pectoris group (SAP group). Another 30 patients with normal coronary angiography at the same period were selected as the control group. The ventricular premature beats were obtained with a 24-hour Holter system. Two indexes, initial oscillatory (TO) and oscillating slope (TS), were calculated. Results The TO of ACS group was significantly higher than that of SAP group and control group (P <0.01), while TS was significantly lower than that of SAP group and control group (P <0.01). Conclusion ACS patients have abnormal HRT phenomenon, the risk of sudden death is high.