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骨髓瘤的治疗目前只能取得部分缓解。为提高治疗效果,现对这方面的经验与教训作一简短的回顾。治疗骨髓瘤最好的药物为苯丙氨酸氮芥(M)与环磷酰胺(C,CP),其他肯定有效的药物有卡氮芥(B,BCNU)、氯乙环己亚硝脲(C,CNU)。强的松(P)与前述药物合用时肯定有效。很可能有效的药物为阿霉素(A,ADR)与长春新碱(V,VCR)。初治M 与 C 均可连续或间歇用药,效果差不多,但后一用法省事,且骨髓抑制发生率低。
Myeloma treatment is only partially relieved. In order to improve the therapeutic effect, a brief review is given of the experience and lessons learned in this respect. The best drugs for the treatment of myeloma are melphalan (M) and cyclophosphamide (C, CP). Other drugs that are definitely effective are carmustine (BCB, BCNU), carbamazamide C, CNU). Prednisone (P) and the aforementioned combination of drugs is certainly effective. Probable drugs are doxorubicin (ADR) and vincristine (V, VCR). Initial treatment of M and C can be continuous or intermittent medication, the effect is similar, but the latter used to save trouble, and the incidence of bone marrow depression is low.