阿托品是M胆碱受体阻断药。大剂量阿托品注射是有机磷中毒解救的重要措施。阿托品要足量和反复持续应用,对于严重中毒昏迷患者,更需要大剂量使用使之出现“阿托品化”[1]。阿托品化即临床出现瞳孔较前扩大,口干,皮肤干燥和颜面潮红,肺部湿啰音消失及心率加快等［2]。中毒解救时 Atropine is a cholinergic receptor blocker. High-dose atropine injection is an important measure to rescue organophosphate poisoning. Atropine to adequate and repeated continuous application, for patients with severe poisoning coma, but also the need for high-dose use of “atropine” [1]. Atropine is the clinical appearance of the pupil than the previous expansion, dry mouth, dry skin and facial flushing, pulmonary wet rales and heart rate disappear [2]. Poisoning rescue