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目的对胺碘酮在老年人心肌梗死后室性心律失常中的临床治疗效果予以探讨。方法 80例心肌梗死后室性心律失常患者,随机分为对照组和研究组,各40例。对照组患者采用利多卡因进行治疗,研究组采用胺碘酮进行治疗,比较治疗后两组患者24 h内室性心律失常发作次数、QRS波时间、心率等变化情况和治疗效果。结果治疗后,研究组患者显效35例,有效3例,无效2例,总有效率为95%;对照组患者显效26例,有效4例,无效10例,总有效率为75%。研究组总有效率高于对照组,差异有统计学意义(P<0.05)。研究组室性心律失常发作次数、QRS波时间及心率均优于对照组,差异有统计学意义(P<0.05)。结论胺碘酮可以有效治疗心肌梗死后室性心律失常,改善心功能指标,提高患者生活质量,是临床上治疗心肌梗死后室性心律失常的理想药物,值得在临床上大力推广使用。
Objective To investigate the clinical effect of amiodarone on ventricular arrhythmias after myocardial infarction in the elderly. Methods Eighty patients with ventricular arrhythmia after myocardial infarction were randomly divided into control group and study group, 40 cases in each group. Patients in the control group were treated with lidocaine. The study group was treated with amiodarone. The incidence of ventricular arrhythmia episodes, QRS wave time, heart rate and other changes in 24 hours after treatment were compared between the two groups. Results After treatment, the study group was markedly effective in 35 cases, effective in 3 cases, invalid in 2 cases, the total effective rate was 95%; control group of patients markedly effective in 26 cases, effective in 4 cases, ineffective in 10 cases, the total effective rate was 75%. The total effective rate of the study group was higher than that of the control group, the difference was statistically significant (P <0.05). The number of ventricular arrhythmia episodes, QRS wave time and heart rate in the study group were better than those in the control group, with significant difference (P <0.05). Conclusions Amiodarone can effectively treat ventricular arrhythmia after myocardial infarction, improve cardiac function and improve quality of life of patients. It is an ideal drug for clinical treatment of ventricular arrhythmia after myocardial infarction and is worthy of promotion in clinic.