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目的:回顾性分析20 180例液基薄层细胞学检测系统(TCT)检测结果,以评估该技术在宫颈疾病筛查中的价值。方法:随机选取2009年1月至2011年7月期间来我院体检人员共计20 180例TCT检测结果,分不同年龄段统计TCT异常的比例,并和相应的病理学诊断比较,了解TCT的诊断符合率。结果:在20 180例标本中共有1 080例有异常TCT报告,阳性率约为5.35%,年龄20~50岁之间,TCT阳性率要高于其他年龄段,但50岁后随年龄的递增TCT阳性检出率逐渐下降。在445例不能明确诊断意义的不典型鳞状细胞(A SCU S)中,病理检查结果的阳性率为9.89%,145例倾向上皮内高度病变的不典型鳞状细胞(A SC-H)的阳性率为76.56%,219例低级别鳞状上皮内病变(LS IL)的阳性率90.0%,225例高度鳞状上皮内病变(HS IL)阳性率为100%,24例癌和病理报告完全符合。22例非典型腺细胞(AGC)的阳性率为63.6%,但AGC中有两例为子宫内膜癌。结论:TCT是一种有效的宫颈癌筛查技术,规范化操作能提高该技术对宫颈疾病的筛查准确率,有助于及时发现并治疗宫颈癌前病变,达到有效的预防效果。
OBJECTIVE: To retrospectively analyze the results of 20 180 liquid-based thin-layer cytology (TCT) tests to assess the value of this technique in cervical disease screening. Methods: A total of 20 180 TCT results from our hospital from January 2009 to July 2011 were randomly selected. The proportion of TCT abnormalities in different age groups was statistically analyzed and compared with the corresponding pathological diagnosis to understand the diagnosis of TCT In line with the rate. Results: There were altogether 1080 cases of abnormal TCT in 20 180 samples, the positive rate was about 5.35%. The positive rate of TCT was higher than that of other age groups between 20 and 50 years old, but increased with age after 50 years TCT positive detection rate decreased gradually. In 445 cases of atypical squamous cells (A SCU S) of undetermined diagnostic significance, the positive rate of pathological examination was 9.89%, and 145 cases of atypical squamous cells (A SC-H), which tended to be highly intraepithelial lesions The positive rate was 76.56%. The positive rate of LSIL in 219 cases was 90.0%, and the positive rate of HSIL in 225 cases was 100%. The complete report of 24 cases of carcinoma and pathology meets the. The positive rate of 22 atypical glandular cells (AGC) was 63.6%, but two of the AGCs were endometrial cancers. Conclusion: TCT is an effective screening technique for cervical cancer. Standardized operation can improve the screening accuracy of cervical cancer and help to detect and treat cervical precancerous lesions in time and achieve effective preventive effect.