论文部分内容阅读
目的评价体外放射治疗治疗宫颈癌的近期及远期疗效。方法选取2005年1月至2007年6月间收治的首次体外放射治疗宫颈癌患者56例,按照随机对照表法将所有患者分为放射治疗A组和放射治疗B组,每组28例,两组患者均先行全身静脉化疗再行体外放射治疗,放射治疗A组的挡铅高度到达子宫底上1.0~1.5cm,而放射治疗B组为全腔野高度。结果 A组和放射治疗B组的总有效率分别为85.7%和78.6%,差异无统计学意义(P=0.132)。两组3和5年生存率、放射性膀胱炎和直肠炎发生率比较,差异均无统计学意义(P<0.05)。放射治疗A组的盆腔淋巴结转移率明显低于放射治疗B组(P<0.001)。结论盆腔野正中挡铅4 cm宽度,高度至子宫底上1.0~1.5cm体外放射治疗,疗效确切,可有效减少盆腔淋巴结转移。
Objective To evaluate the short-term and long-term effects of in vitro radiotherapy for cervical cancer. Methods Fifty-six patients with cervical cancer who were treated with external beam radiotherapy from January 2005 to June 2007 were selected. All patients were divided into radiotherapy group A and radiotherapy group B according to the randomized control table method, with 28 cases in each group. Group patients were treated with systemic intravenous chemotherapy followed by external beam radiotherapy. The height of lead blockade in group A was 1.0-1.5 cm at the bottom of the uterus, and that of radiation therapy group B was total cavity height. Results The total effective rates of group A and group B were 85.7% and 78.6%, respectively, with no significant difference (P = 0.132). There were no significant differences in the 3-year and 5-year survival rates, radiological cystitis and proctitis between the two groups (P <0.05). Radiotherapy group A pelvic lymph node metastasis was significantly lower than radiotherapy B group (P <0.001). Conclusions The pelvic midline block lead 4 cm wide, high to the uterus 1.0-1.5cm in vitro radiotherapy, the exact effect, can effectively reduce the pelvic lymph node metastasis.