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目的探讨LDL-C/HDL-C、TG/HDL-C比值与冠心病预后相关性。方法收集68例经冠脉造影确诊的冠心病患者(CHD)及57例冠脉造影阴性者(对照组),冠造前空腹12小时后清晨采集血样上机测定血脂,并计算出LDL-C/HDL-C比值、TG/HDL-C比值。结果CHD组患者LDL-C和TG与HDL-C比值水平及异常率均明显高于对照组,相关分析显示,LDL-C/HDL-C比值及TG/HDL-C比值与冠心病相关,LDL-C/HDL-C比值与冠心病回归关系更强,且两比值之间呈正相关。结论LDL-C/HDL-C及TG/HDL-C比值可作为预测CHD的指标。与TG/HDL-C相比,LDL-C/HDL-C比值水平与冠心病相关更强。
Objective To investigate the relationship between LDL-C / HDL-C, TG / HDL-C ratio and the prognosis of coronary heart disease. Methods Sixty-eight patients with coronary heart disease (CHD) and 57 patients with negative coronary angiography (CHD) diagnosed by coronary angiography were collected. Blood samples were taken from the anterior fasten for 12 hours before crowning for determination of blood lipids and LDL-C / HDL-C ratio, TG / HDL-C ratio. Results The levels of LDL-C, TG and HDL-C in CHD group were significantly higher than those in control group. The correlation analysis showed that the ratio of LDL-C / HDL-C and the ratio of TG / HDL-C were correlated with coronary heart disease. The correlation between -C / HDL-C and coronary heart disease was stronger, and there was a positive correlation between the two ratios. Conclusions LDL-C / HDL-C and TG / HDL-C ratios can be used as predictors of CHD. Compared with TG / HDL-C, the level of LDL-C / HDL-C is more correlated with coronary heart disease.