既往研究表明:克山病病区与非病区水土粮中某些微量元素含量有差异及年度差异,而只有锰,病区高于非病区且无年度变化,病人血清锰、发锰,特别是低硒地区病人血清锰,均高于同地区的健康人;而锰又可作用于心肌细胞膜的慢通道,影响心脏的功能。由此不难设想, Previous studies have shown that there are differences and annual differences in some trace elements contents between Keshan disease and non-endemic areas, but only manganese is higher than that in non-disease and no annual changes. The levels of serum manganese, manganese, In particular, patients with low selenium serum manganese, were higher than healthy people in the same area; and manganese can act on the slow channel of myocardial cell membrane, affecting the heart’s function. It is not difficult to imagine,