化疗导致的卵巢功能不全影响着患者的生活质量。长期以来,通常采用激素替代疗法治疗绝经问题,但考虑到雌激素会增加乳腺癌妇女癌症复发的危险,因此,医生必须采用其他方法替代治疗。本文主要讨论几种新的治疗方法,通过改变卵巢上皮对细胞毒药物的敏感性,达到无症状控制,避免发生骨折、不孕症等副作用。 Chemotherapy-induced ovarian insufficiency affects the patient’s quality of life. Hormone replacement therapy is commonly used to treat menopause for a long time, but given that estrogen increases the risk of cancer recurrence in women with breast cancer, other alternatives to treatment must be used by the doctor. This article focuses on several new treatment methods, by changing the epithelial ovarian epithelial sensitivity to cytotoxic drugs to achieve asymptomatic control, to avoid the occurrence of fractures, infertility and other side effects.