组织细胞坏死性淋巴结炎是一种少见的、良性的疾病 ,病因和发病机制尚不十分明确 ,临床表现缺乏特异性 ,且儿童病例少见 ,给诊断和鉴别诊断带来了一定的困难。该文参考了近年来国内外的文献 ,对其病因、发病机制、病理改变、诊断等方面的研究进展进行阐述 Tissue necrotic lymphadenitis is a rare and benign disease, the etiology and pathogenesis are not yet clear, the clinical manifestations of the lack of specificity, and rare cases of children, to the diagnosis and differential diagnosis has brought some difficulties. This paper refers to the literature in recent years at home and abroad, elaborates on the research progress of its etiology, pathogenesis, pathological changes, diagnosis and so on