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目的分析脑出血患者急性期血液流变学指标的变化及其临床意义。方法选88例符合标准的病人,检测其血液流变学指标,按出血量、有无合并脑梗塞、有无合并高血压、病情等分组分析。结果纤维蛋白原、全血还原粘度低切高于正常参考值,但红细胞压积明显低于正常值。纤维蛋白原指标在病程长、合并脑梗塞、病情轻时偏高,组间比较差异有统计学意义(P<0.01~0.05)。全血还原粘度在出血量少组偏高,组间比较差异有统计学意义(P<0.05)。全血粘度、血浆粘度在合并高血压病组偏高,组间比较差异有统计学意义(P<0.05)。结论脑出血患者急性期的血液流变学指标与病程、病情、出血量相关。
Objective To analyze the changes and clinical significance of hemorheology in patients with cerebral hemorrhage in acute stage. Methods Eighty-eight patients with standard criteria were selected and their hemorrheological parameters were measured. The patients were divided into groups according to the amount of bleeding, the presence or absence of cerebral infarction, the presence or absence of hypertension, and the condition of the patients. Results Fibrinogen, whole blood reduced viscosity cut low than the normal reference value, but hematocrit was significantly lower than normal. Fibrinogen index in the long course of disease, with cerebral infarction, the condition of light high, the difference between the two groups was statistically significant (P <0.01 ~ 0.05). Reduced viscosity of whole blood in the group of high blood loss, the difference between the two groups was statistically significant (P <0.05). Whole blood viscosity and plasma viscosity were higher in patients with hypertension, the difference between the two groups was statistically significant (P <0.05). Conclusion The hemorheological indexes of acute cerebral hemorrhage patients are related to the course of disease, illness and bleeding volume.