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成年雌性Ｗｉｓｔａｒ大鼠３０只，体重２４０±２６．５ｇ，等分为Ⅰ、Ⅱ、Ⅲ３个组。各组蛋白质分别占饲料的４０％，２０％和８％。饲养４３天（受孕前２１天），观察饲料中蛋白质水平对胚胎期大鼠脑发育的影响。结果表明，新生幼鼠体重和脑重，Ⅰ组最重，分别为６．９５ｇ和２４０．９ｍｇ；Ⅱ组次之，分别为６．５７ｇ和２３７．８ｍｇ，Ⅲ组最轻，分别为５．６２ｇ和２１０．９ｍｇ。各组间体重均有显著差别（Ｐ＜０．０１），Ⅲ组脑重明显低于Ⅰ、Ⅱ组（Ｐ＜０．０１）。各组脑中蛋白质含量依次为１０．０３ｍｇ、９．０９ｍｇ和７．４６ｍｇ（Ｐ＜０．０１或＜０．０５），脑中ＤＮＡ和ＲＮＡ水平以及每ｇ脑组织中ＲＮＡ含量也是Ⅰ组最高，Ⅲ组明显低于其它两组。说明蛋白质水平不同对大鼠胚胎期脑生长发育有一定影响。
Thirty adult female Wistar rats weighing 240 ± 26.5g were equally divided into three groups Ⅰ, Ⅱ and Ⅲ. Each group of proteins accounted for 40%, 20% and 8% of feed, respectively. The animals were kept for 43 days (21 days before conception) to observe the effects of protein levels in the diet on brain development in embryonic rats. The results showed that the body weight and brain weight of the newborn rats were the heaviest in group Ⅰ, 6.95g and 240.9mg, respectively, followed by those of group Ⅱ 6.57g and 237.8mg, the lightest ones in group Ⅲ were 5 and 5 respectively. 62g and 210.9mg. The body weight of each group was significantly different (P <0.01), and the brain weight of group Ⅲ was significantly lower than that of group Ⅰ and Ⅱ (P <0.01). The protein contents of brain in each group were 10.03mg, 9.09mg and 7.46mg (P <0.01 or <0.05), and the brain DNA and RNA levels and the RNA content in each g brain were the highest in group Ⅰ , Ⅲ group was significantly lower than the other two groups. Explain that different protein levels have some effect on brain growth and development in rat embryonic stage.