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目的探讨腹腔镜胆囊切除术(LC)对意外性胆囊癌的影响。方法回顾性分析经术后病理证实为胆囊癌者21例临床资料,其中11例行腹腔镜胆囊切除术(LC),10例行开放性胆囊切除术(OC),对比两组累积存活比率和5个预后因素,包括组织分级、病理分期、胆汁溢出发生率、手术类型以及附加的外科治疗。结果8例(72.7%)LC术后及7例OC术后(70.0%)出现肿瘤复发,两者差异无统计学意义(P=0.86),两组均无腹壁转移。生存率与肿瘤分期和胆汁溢出有关(P=0.006和P=0.003),生存率与上述两种手术方式无关(P=0.74)。结论LC不影响意外性胆囊癌的预后。
Objective To investigate the effect of laparoscopic cholecystectomy (LC) on unexpected gallbladder cancer. Methods The clinical data of 21 cases with gallbladder carcinoma confirmed by postoperative pathology were analyzed retrospectively. Among them, 11 cases underwent laparoscopic cholecystectomy (LC) and 10 cases underwent open cholecystectomy (OC). The cumulative survival rate Five prognostic factors included histologic grade, pathological stage, incidence of bile spill, type of surgery, and additional surgical treatment. Results Tumor recurrence occurred in 8 cases (72.7%) after LC and in 7 cases after OC (70.0%). There was no significant difference between the two groups (P = 0.86). There was no abdominal wall metastasis in both groups. Survival rate was related to tumor stage and bile spill (P = 0.006 and P = 0.003). Survival rate was not related to the above two surgical methods (P = 0.74). Conclusion LC does not affect the prognosis of unexpected gallbladder cancer.