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作者对1994年8月31日至1995年2月28日瑞典一大学医院有控制超促排卵及体外授精（COH-IVF）的428例病例进行了研究，按Golan等标难时发生OHSS病人进行分类。八组18例为重度（）HSS；B组og倒包括所有轻、中、重OHSS病例；C组78例包括OHSS没有病危因素者；D组192例所有OHSS及有危险因素者。提示OHSS高危因素指血中E。水平迅速增高，在注射hCG当日E。水平＞IOnmol／L，或两侧卵巢中直径＞15mm大卵泡＞15个以上，件恶心、腹肌紧张，抽吸采卵卵泡数＞15个或至少＞25个卵泡平均直径为12～15mm，在抽吸卵泡至ET期间腹部不适。有OHSS高危因素者在buseriln降调后减少FSH及hMG剂量，采卵或ET时补充白蛋白（4gIV），以黄体酮替代hCG支持黄体至ET或胚胎冷冻。D组危险因素指ET后出现持续恶心及腹部疼痛，这类病人用黄体酮50mg／dlm支持黄体并行妊娠试验，若ET后18～20天尿妊娠试验阳性（hCG＞4OIU／L），黄体酮连续应用至少4周。刺激卵泡发育可单用hCG或FSH或两者并用，剂量为7S～225IU／d，每l～3天检测EZ水平，每周阴道超声检测卵泡发育，根据EZ水平及超声结果调整药物剂量。当＞3个卵泡直径达18～20mm时，应用hCGS000～1000OIU促卵泡成熟，34～38h后阴道超声下取卵。取卵当日及ETZ～3天分别给予hCG2500IU支持黄体，
The authors studied 428 cases of super-Ovulation and In-vitro Fertilization (COH-IVF) controlled at a Swedish University Hospital from August 31, 1994 to February 28, 1995. OHSS patients were treated according to Golan’s criteria classification. Eight of the 18 patients were severe () HSS; Group B og down included all cases of mild, moderate and severe OHSS; 78 patients of Group C included no risk factors for OHSS; and 192 patients of all OHSS and risk factors of Group D. Prompt OHSS risk factors in the blood E. Rapid increase in the level of hCG on the day of injection. > 15nm or more in the ovary> 15mm in diameter, nausea, abdominal muscle tension, aspiration follicle count> 15 or at least> 25 follicles with an average diameter of 12 ~ 15mm, Abdominal discomfort during aspiration of follicles to ET. Patients with a high risk of OHSS had reduced FSH and hMG doses after buseriln down-regulation, albumin (4gIV) during ovum or ET, and progesterone replacement hCG to support luteal phase to ET or embryo freezing. D group of risk factors for nausea and abdominal pain after the emergence of ET, such patients with progesterone 50mg / dlm support luteal concurrent pregnancy test, if 18 to 20 days after ET pregnancy test positive (hCG> 4OIU / L), progesterone Apply continuously for at least 4 weeks. Stimulation of follicular development can be used alone hCG or FSH or a combination of both, the dose of 7S ~ 225IU / d, every 1 to 3 days to detect EZ levels, vaginal ultrasound detected follicular development weekly, according to the EZ level and ultrasound results to adjust the drug dose. When> 3 follicles up to 18 ~ 20mm in diameter, the application of hCGS000 ~ 1000OIU follicles mature follicles after 34 ~ 38h ovulation. Ovulation day and ETZ ~ 3 days were given hCG2500IU support corpus luteum,