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目的:评价血必净注射液与青霉素联用治疗小儿感染性心内膜炎患者的临床疗效。方法:选取2014年10月—2015年10月期间收治的小儿感染性心内膜炎患者60例,按治疗方法不同将其分成对照组与观察组,每组30例,对照组均给予青霉素治疗,观察组均给予青霉素与血必净注射液联用治疗,比较两组患者治疗后的临床疗效。结果:观察组患者治疗后的体温、白细胞计数优于对照组(P<0.05);其赘生物的缩小率、病死率均小于对照组(P<0.05)。结论:采用血必净注射液与青霉素联用治疗小儿感染性心内膜炎患者,临床效果较显著,具有协同作用,优于单用青霉素的疗效。
Objective: To evaluate the clinical efficacy of Xuebijing injection combined with penicillin in the treatment of pediatric infective endocarditis. Methods: Sixty cases of children with infective endocarditis admitted from October 2014 to October 2015 were selected and divided into control group and observation group according to different treatment methods. Each group was given 30 cases of penicillin , The observation group were given penicillin and Xuebijing injection combined with treatment, the clinical efficacy of the two groups were compared. Results: The body temperature and white blood cell count of the observation group were better than those of the control group (P <0.05). The shrinkage rate and mortality of the neoplasm in the observation group were less than those in the control group (P <0.05). Conclusion: Xuebijing injection combined with penicillin in the treatment of children with infective endocarditis in clinical efficacy is more significant, with synergistic effect, superior to penicillin alone.