高聚生(highlyagglutinativestaphylococcin,HASL)是近年来应用于临床的新型抗肿瘤生物反应调节剂。我们自2002年1月～2004年2月,采用胸腔微创置管引流灌注高聚生和顺铂治疗恶性胸水取得较好疗效,现报告如下:1材料方法1.1一般资料经胸水脱落细胞学检查为阳性的肺癌、乳腺癌和胸 Highly aggregate (highlyagglutinativestaphylococcin, HASL) is a new type of antitumor biological response modifier used clinically in recent years. We have from January 2002 to February 2004, the use of thoracic minimally invasive drainage catheter hyperplasia and cisplatin treatment of malignant pleural effusion and achieved good results, are as follows: 1 Materials and Methods 1.1 General information by the pleural effusion cytology was positive Lung, breast and chest