帕金森病(PD)又名震颤麻痹,是一种常见的中老年人神经系统的进行性变性疾病。它的主要病变发生在中脑黑质等处,由于黑质细胞的变性坏死导致脑内神经递质多巴胺的缺乏,从而引起静止性震颤、肌强直、运动迟缓等一系列的临床症状。PD的发病率在整体人群中为0.1%,在65岁以上人群达1 Parkinson’s disease (PD), also known as Parkinsonism paralysis, is a common progressive degenerative disease of the nervous system of the elderly. Its main lesion occurs in the substantia nigra and other places, due to degeneration and necrosis of the substantia nigra leads to the lack of dopamine, a neurotransmitter in the brain, causing a series of clinical symptoms such as resting tremor, myotonia, and bradykinesia. The incidence of PD is 0.1% in the general population and 1 in those over 65 years of age