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雷米封(INH)在1952年首次推广应用后,以它杀菌力强,毒力小,口服便利,剂量小,生产容易价格低和在出现耐药菌后耐药菌毒力减低的优点在结核科广泛使用。INH除可引起未梢神经炎外,尚可引起神经精神症状。本文报告5例。例1,冯某,男,42岁,Ⅲ型肺结核,慢性肝炎。1988—10—17入院。用INH、链霉素(SM),乙胺丁醇(EMB)抗结核治疗。2周后发现病人健谈。自述有不平常经历。生活不规则,违返院规喝啤酒,每日2瓶;打扑克;每日夜间11点才休息。住院期间告
When INH was first introduced in 1952, it has the advantages of strong bactericidal power, low virulence, convenient oral administration, low dosage, low production cost, and reduced virulence of resistant bacteria after emergence of resistant bacteria. Tuberculosis widely used. In addition to INH can cause peripheral neuritis, can still cause neuropsychiatric symptoms. This article reports 5 cases. Example 1, Fengmou, male, 42 years old, type III tuberculosis, chronic hepatitis. 1988-10-17 admitted to hospital. With INH, streptomycin (SM), ethambutol (EMB) anti-TB treatment. 2 weeks after the discovery of patient talkative. Self-report has an unusual experience. Irregular life, back to the hospital to drink beer, 2 bottles a day; play poker; rest at 11 o’clock every night. Inpatient notice