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目的:探讨埃索美拉唑三联疗法治疗幽门螺杆菌阳性消化性溃疡的临床效果。方法:选取46例幽门螺杆菌阳性消化性溃疡患者,分为观察组和对照组。观察组采用埃索美拉唑联合阿莫西林、克拉霉素治疗;对照组患者采用传统的奥美拉唑联合阿莫西林、克拉霉素治疗。对比两组患者的治疗效果。结果:观察组和对照组的溃疡治愈率和Hp根除率相对比均无显著性差异,但是观察组治疗疗程短,治疗费用低。结论:以埃索美拉唑为基础的三联1周疗法,效果好,疗程短,治疗成本低,值得推广。
Objective: To investigate the clinical efficacy of esomeprazole triple therapy in the treatment of Helicobacter pylori-positive peptic ulcer. Methods: 46 cases of H. pylori positive peptic ulcer patients were divided into observation group and control group. The observation group was treated with esomeprazole combined with amoxicillin and clarithromycin, while the control group was treated with traditional omeprazole combined with amoxicillin and clarithromycin. Compare the treatment effect of two groups of patients. Results: There was no significant difference between the observation group and the control group in the cure rate of ulcer and the eradication rate of Hp, but the observation group had short treatment course and low cost of treatment. CONCLUSION: Esomeprazole-based triple therapy for 1 week has good effect, short course of treatment and low cost of treatment and is worth promoting.