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目的:研究探讨中药滋补汤协助临床治疗强直性脊柱炎的药理学疗效。方法:将符合纳入标准的320例AS患者,随机分为观察组和对照组。观察组180例,对照组140例,观察组首先采用中药滋补汤治疗(主要药物:杜仲、白术、独活、防己、伸筋草、桑寄生),每日1剂,水煎,分2次温服。再进行牵引治疗:颈牵患者取卧位或坐位,用布枕颌托的前方托住下颌,后方托住枕骨结节部进行了牵引。卧位时枕颈部加枕垫。牵引重量一般为5～10kg为宜,时间30min为宜,每日可牵1～3次。对照组单纯口服正清风痛宁片,1日3次,1次2片。两组均治疗8周观察疗效。结果:观察组治疗后取得临床痊愈率、总有效率分别为66.7%、91.7%,而对照组分别为30.0%、54.3%,二者比较有显著差异性(△P<0.05)。结论:中药滋补汤协助临床治疗强直性脊柱炎,并进行药理学研究,取得显著的治疗效果。
Objective: To study the pharmacological effects of traditional Chinese medicine tonic soup on clinical treatment of ankylosing spondylitis. Methods: 320 patients with AS who meet the inclusion criteria were randomly divided into observation group and control group. 180 cases in the observation group and 140 cases in the control group were treated with Chinese medicine tonic soup (main drugs: Eucommia, Atractylodes, clothes. Then traction treatment: cervical traction patients to take the supine or sitting position, with the front of the pillow supporting the mandibular jaw support the rear occipital nodular propulsion. Sleeve neck pillow plus pillow. Traction weight is generally 5 ~ 10kg is appropriate, time is appropriate 30min, daily can be held 1 to 3 times. The control group was given orally Qingfengtongning tablets orally, 3 times on the 1st and once on the 2nd. Both groups were treated for 8 weeks to observe the curative effect. Results: The clinical cure rate in the observation group was 66.7% and 91.7%, respectively, while the control group was 30.0% and 54.3% respectively. There was significant difference between the two groups (P <0.05). Conclusion: Chinese medicine tonic soup for clinical treatment of ankylosing spondylitis, and pharmacological studies, and achieved significant therapeutic effect.