同一例患者发生骨髓增殖性疾病和淋巴增殖性疾病很少见,但报告正日渐增多。最近注意到,在一些过去未接受任何治疗的患者中,上述两种疾病同时或相继自发地发生。本文报道4例混合性淋巴和骨髓增殖性疾病患者。例1,女,77岁。患毛细胞性白血病和急性粒单白血病(AML-M_4)。因年龄大而未用细胞毒剂治疗。入院后2个月发生下呼吸道感染而死亡,未作尸检。例2,男,74岁。于白血病期患淋巴细胞性淋巴瘤和慢性粒单自血病(CMML),因肺部感染曾用抗生素治疗,但未给细胞毒剂。后因心包渗液而死亡,其诊断 The same patient with myeloproliferative disorders and lymphoproliferative disorders is rare, but reports are on the rise. Recently, it has been noted that in some patients who have not undergone any treatment in the past, the above two diseases occur spontaneously or simultaneously. This article reports 4 patients with mixed lymphoid and myeloproliferative disorders. Example 1, female, 77 years old. Suffering from hairy cell leukemia and acute myeloid leukemia (AML-M_4). Because of their age without cytotoxic treatment. 2 months after admission, lower respiratory tract infection and death, no autopsy. Example 2, male, 74 years old. In leukemia patients with lymphocytic lymphoma and chronic myelomonocytic leukemia (CMML), had been treated with antibiotics for lung infections, but did not give cytotoxic agents. After the pericardial effusion and death, the diagnosis