原发性硬化性胆管炎(PSC)的病因尚不了解,其特征为肝内与肝外胆管的纤维化和炎症PSC通常见于炎症性肠病(IBD)。内窥镜逆行性胆管造影术(ERCP)的发展与广泛应用,使我们能比10年前远为较多地诊断这一疾病。在大多数溃疡性结肠炎(UC)同时累及肝胆系统的患者,能够检出PSC。胆汁瘀积性肝功能试验通常呈异常,但患者并无肝脏疾病的症状。肝穿刺所见可提示 The etiology of primary sclerosing cholangitis (PSC), which is characterized by intrahepatic and extrahepatic biliary fibrosis and inflammation, is commonly found in inflammatory bowel disease (IBD). The development and widespread use of endoscopic retrograde cholangiopancreatography (ERCP) has enabled us to diagnose the disease far more than 10 years ago. In most patients with ulcerative colitis (UC) involving the hepatobiliary system, PSC can be detected. Cholestatic liver function tests are usually abnormal, but patients have no symptoms of liver disease. Liver puncture see can be prompted