醋柳酯(Guacetisal),化学名:2-乙酰氧基苯甲酸(2-甲氧基)苯酯,系1979年意大利上市的新药,具有镇咳祛痰作用,剂型有乳剂、胶囊剂及栓剂,对婴儿很适用。本品早于1939年即已合成,但具体合成方法及理化常数未曾查见。我们以乙酰水杨酸为原料,经氯化制得乙酰水杨酰氯,然后在吡啶存在下,于惰性溶剂中与愈创木酚缩合或与愈 Guacetisal, a chemical name of 2-acetoxybenzoate (2-methoxy) phenyl ester, is a new drug marketed in Italy in 1979. It has antitussive and expectorant effects, and its dosage forms include emulsion, capsule and suppository , Suitable for babies. This product has been synthesized as early as 1939, but the specific synthetic methods and physical and chemical constants have not checked. We use acetylsalicylic acid as raw material, chlorinated acetylsalicyloyl chloride, and then in the presence of pyridine, in an inert solvent with guaiacol condensation or more