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支气管哮喘患者都有支气管上皮损伤。鼻息肉在哮喘患者中的发病率较高。本研究的目的是探讨鼻息肉是否也有类似的上皮损伤。从30名原发性鼻息肉患者取得手术切除的鼻息肉标本,其中20例有哮喘,12例有阿司匹林特异反应性;另由8名鼻中隔手术患者取得正常鼻粘膜;由8名鼻息肉合并囊性纤维病患者取得鼻息肉标本,进行对比。组织切片后用光镜检查。上皮损伤的程度按受损面积的百分数表示:0级与正常上皮相似,上皮各层均完好;1级上皮保留2层或2层以上细胞,但不若正常者多;2级上皮只有1层细胞;3级上皮细胞消失。28名鼻息肉患者的息肉标本都有不同程度的
Bronchial asthma patients have bronchial epithelial damage. Nasal polyps in the incidence of asthma in patients with higher. The purpose of this study was to investigate whether nasal polyps also have similar epithelial lesions. Surgical specimens of nasal polyps were obtained from 30 patients with primary nasal polyps, of whom 20 had asthma, 12 had aspirin-specific reactivity, and 8 had nasal septum surgery to obtain normal nasal mucosa. Eight nasal polyps, Patients with sexually transmitted diseases, nasal polyps specimens were compared. Tissue sections with light microscopy. The extent of epithelial damage is expressed as a percentage of damaged area: Grade 0 is similar to normal epithelium with intact epithelial layers; Grade 1 epithelium retains two or more layers of cells, but not as normal; grade 2 epithelial only has one layer Cells; grade 3 epithelial cells disappear. 28 polyps in patients with nasal polyps have varying degrees of polyp specimens