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对急诊收治的２８例静脉注射二氢埃托啡（ＤＨＥ）致急性中毒病人的诊断及治疗进行总结讨论．结果提示ＤＨＥ若应用不当可造成呼吸严重抑制、低氧血症、酸中毒、休克、脉管栓塞及多脏器功能损害；一次剂量过大可致呼吸骤然停止；解救不及时病人可死于呼吸或多脏器功能衰竭．临床上依据①青少年突发昏迷；②用过“口含片”，有呼吸抑制、瞳孔缩小及缺氧症；③较多静脉针痕及脉管栓塞硬化；④纳洛酮有特效拮抗等特征进行诊断．临床救治以迅速解除呼吸抑制、氧疗及保护生命器官功能为主．
The diagnosis and treatment of 28 cases of acute poisoning caused by intravenous administration of dihydroetorphine (DHE) in emergency department were summarized. The results suggest that improper application of DHE can cause severe respiratory depression, hypoxemia, acidosis, shock, vaso-embolism and multiple organ dysfunction; a dose can cause sudden respiration; rescue not timely death in patients with respiration Or multiple organ failure. Clinical basis ① adolescent sudden unconscious; ② used “buccal tablets”, respiratory depression, miosis and hypoxia; ③ more venous needle marks and vascular embolization; ④ naloxone antagonist and other characteristics of the special Diagnose. Clinical treatment to quickly relieve respiratory depression, oxygen therapy and protection of vital organs function.