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醒脑静注射液为目前临床常用的一种中药急救制剂,属于医疗保险和农村医疗保险支付比例较高的中药注射剂,临床应用广泛。但不良反应(ADRs)的病例报道日趋增多。临床调配时,常用5%-10%GS注射液或0.9%NS注射液作为溶媒稀释。在静脉调配过程中,发现使用5%-10%GS注射液调配时产生很多气泡,而使用0.9%NS注射液作为溶媒则很少气泡。因此,笔者对醒脑静注射液分别溶于5%GS注射液、10%GS注射液和0.9%NS注射液进行不溶性微粒和p H检查,考察其配伍后输液的稳定性,为临床合理用药提供参考。
Xingnaojing injection is a traditional Chinese medicine first aid preparation commonly used in clinical practice. It belongs to the traditional Chinese medicine injection which is paid by medical insurance and rural medical insurance and has a wide range of clinical applications. However, the number of cases of adverse reactions (ADRs) is increasing. Clinical deployment, commonly used 5% -10% GS injection or 0.9% NS injection as a solvent dilution. During the IV deployment, many cells were found to be infused with 5% to 10% GS injection, whereas 0.9% NS injection was less bubbled. Therefore, the author of Xingnaojing injection were dissolved in 5% GS injection, 10% GS injection and 0.9% NS injection of insoluble particles and p H examination, to investigate the compatibility of infusion stability for the clinical rational use of drugs for reference.